Why Choose Vitadefence Nattokinase Multi with Vitamin D3 and Selenium?

Cardiovascular health is foundational to overall wellness. Your circulatory system works 24/7, delivering oxygen and nutrients to every cell while removing waste products. Supporting this complex system requires more than just exercise and diet—targeted nutritional support can play a valuable role. Our Vitadefence Nattokinase Multi combines the traditional Japanese enzyme nattokinase with vitamin D3, selenium, and a carefully selected blend of botanicals to create a comprehensive cardiovascular support formula.

What is Nattokinase?

Nattokinase is a proteolytic enzyme extracted from natto, a traditional Japanese food made from fermented soybeans. The Japanese have consumed natto for over 1,000 years, and it remains a dietary staple in Japan today.

Our formula provides 100mg of nattokinase delivering 2000 Fibrinolytic Units (FU) per capsule—a substantial, research-relevant dose of this unique enzyme.

The nattokinase in our formula is derived from fermented soybean extract and is measured in Fibrinolytic Units, which indicates its enzymatic activity level.

Understanding Fibrinolytic Units

Fibrinolytic Units (FU) measure the enzymatic activity of nattokinase. The higher the FU, the more active the enzyme. Our 2000 FU per capsule represents a meaningful therapeutic dose commonly used in research studies.

Many nattokinase supplements on the market provide much lower FU amounts. Our 2000 FU per capsule ensures you're getting a clinically relevant dose.

The Complete Cardiovascular Support Formula

What Each Capsule Provides:

Primary Ingredients:

• Nattokinase (from fermented soybean extract): 100mg (providing 2000 Fibrinolytic Units)
• Black Seed Extract (Nigella Sativa): 250mg
• Carrageen Sea Moss Extract (Chondrus Crispus): 250mg
• Green Tea Extract (Camellia Sinensis): 150mg
• Dandelion Root Extract (Taraxacum Officinale): 50mg
• N-Acetyl Cysteine (NAC): 40mg
• Coriander Leaf Powder (Cilantro): 30mg
• Fennel Seed Extract (Foeniculum Vulgare): 30mg
• Vitamin D3 (Vegan, from Cholecalciferol): 5.5μg (220iu) - 110% NRV
• Selenium (as Selenomethionine): 55μg - 100% NRV

NRV = Nutrient Reference Value

The Immune Support Duo

Selenium and Vitamin D both contribute to the normal function of the immune system—your body's natural defense mechanism against daily challenges.

Selenium (at 100% NRV) also contributes to:

• Protection of cells from oxidative stress
• Normal thyroid function

Vitamin D (at 110% NRV) supports immune health while also being essential for numerous other body functions.

The Botanical Synergy

Black Seed (Nigella Sativa) - 250mg

Black seed, also known as black cumin, has been used in traditional practices for thousands of years. Referred to in some cultures as "the seed of blessing," Nigella Sativa has a rich history of traditional use spanning Middle Eastern, Asian, and Mediterranean cultures.

Our formula provides a substantial 250mg of black seed extract per capsule.

Carrageen Sea Moss (Chondrus Crispus) - 250mg

Irish sea moss, or carrageen, is a type of red seaweed harvested from rocky Atlantic coastlines. Rich in minerals and naturally occurring compounds, sea moss has been used traditionally in Ireland and other coastal regions for centuries.

The 250mg dose provides concentrated sea moss benefits without the preparation required for the whole seaweed.

Green Tea Extract (Camellia Sinensis) - 150mg

Green tea is one of the most researched botanicals in the world. Rich in polyphenols, particularly catechins like EGCG (epigallocatechin gallate), green tea has been consumed for millennia in Asian cultures.

Our extract form provides concentrated compounds without the caffeine content of brewed tea.

Dandelion Root Extract (Taraxacum Officinale) - 50mg

Often dismissed as a weed, dandelion has a long history of traditional use. The root, in particular, has been used in European herbal practices for centuries.

N-Acetyl Cysteine (NAC) - 40mg

NAC is a form of the amino acid cysteine and a precursor to glutathione, one of the body's most important antioxidant compounds. NAC has been used in clinical settings and as a supplement for various purposes.

Coriander Leaf (Cilantro) - 30mg

Coriander, the leaf of the cilantro plant, has been used in traditional systems around the world. Beyond its culinary use, it has a history of traditional wellness applications.

Fennel Seed Extract (Foeniculum Vulgare) - 30mg

Fennel seeds have been used since ancient times in Mediterranean and Asian cultures, both as a culinary spice and in traditional wellness practices.

Complete Ingredient Transparency

Full Ingredients List: Nattokinase (SOY), Capsule: Hydroxypropyl Methylcellulose (HPMC), Black Seed Extract (Nigella Sativa), Carrageen Sea Moss Extract (Chondrus Crispus), N-Acetyl Cysteine Powder, Stoneground Brown Rice Flour (Gluten Free) (Oryza Sativa), Coriander Leaf Powder (Cilantro), Dandelion Root Extract (Taraxacum Officinale), Selenomethionine (as Calcium Phosphate), Green Tea Extract (Camellia Sinensis), Fennel Seed Extract (Foeniculum Vulgare), Vitamin D3 (Vegan) (as Cholecalciferol).

Allergy Advice: For allergens, see ingredients in BOLD. Contains soy.

How to Use Nattokinase Multi

Dosage: Take 1 capsule per day, or as advised.

Important Timing: Do not exceed the recommended intake.

Best Practices:

• Can be taken with or without food
• Consistency is key—take daily for best results
• Take at the same time each day to build a routine
• Stay well hydrated throughout the day

Critical Safety Information

Do NOT Take This Product If You Are:

Using blood pressure medication - Nattokinase may interact with blood pressure medications

Using blood thinning medication - Nattokinase has fibrinolytic activity and should not be combined with anticoagulants or antiplatelet drugs including:

• Warfarin (Coumadin)
• Aspirin
• Clopidogrel (Plavix)
• Other anticoagulants or antiplatelet medications

Pregnant or nursing - Not recommended during pregnancy or breastfeeding

Scheduled for surgery - Stop taking at least 2 weeks before any scheduled surgery due to the fibrinolytic activity

Additional Precautions:

Persons taking medication should only consume this product under medical supervision.

Food supplements should not be used as a substitute for a varied diet and healthy lifestyle.

Consult your doctor before taking any food supplement or changing your daily diet.

Who Should Consider Nattokinase Multi?

Those Interested in Cardiovascular Support

Nattokinase has been studied for its unique enzymatic properties and is particularly popular among individuals interested in cardiovascular wellness support.

People Seeking Immune Support

The combination of selenium and vitamin D3 provides dual immune system support—particularly valuable during seasonal changes or periods of increased stress.

Those Following Japanese Wellness Traditions

Natto has been consumed in Japan for over a millennium. For those who appreciate the wisdom of traditional diets but don't enjoy the taste or texture of natto, our capsules provide the enzyme in an easy-to-take form.

Individuals Looking for Comprehensive Botanical Support

With eight different botanical ingredients plus essential nutrients, this formula provides multi-faceted support rather than relying on a single ingredient.

Important Considerations

Not Suitable For:

• Anyone on blood thinning medication (anticoagulants or antiplatelet drugs)
• Anyone on blood pressure medication without medical supervision
• Pregnant or nursing women
• People scheduled for surgery (within 2 weeks)
• People with bleeding disorders
• Those with soy allergies

Requires Medical Supervision If:

• Taking any prescription medications
• Under treatment for cardiovascular conditions
• Have a history of bleeding problems
• Have thyroid conditions (due to selenium content)

Quality and Manufacturing

Manufacturing Excellence

• GMP Certified - Good Manufacturing Practice standards
• Made in the United Kingdom - UK quality standards
• Batch tested - Quality verification for every batch

Dietary Suitability

• ✅ Suitable for Vegans - Including vegan vitamin D3 source
• ✅ HPMC capsules - Vegetarian capsule shells
• ✅ Gluten-free brown rice flour - Safe for gluten-sensitive individuals

Important: While vegan-friendly, this product contains soy (from the fermented soybean extract used to produce nattokinase).

Supply Information

60 capsules per bottle = 60-day supply at standard 1 capsule daily dose

Storage and Handling

To maintain optimal enzyme activity and freshness:

• Store in a cool, dry place
• Keep out of reach of children
• Check the best before date on the base
• Keep bottle tightly sealed
• Avoid exposure to heat and moisture
• Do not refrigerate unless specifically instructed

Understanding Nattokinase's Origins

Natto is created through a specific fermentation process:

1. Soybeans are steamed
2. A beneficial bacteria (Bacillus subtilis natto) is added
3. The mixture ferments for approximately 24 hours
4. During fermentation, the bacteria produces nattokinase enzyme
5. The enzyme is then extracted and purified for supplementation

The resulting food, natto, has a distinctive stringy texture, strong smell, and acquired taste—which is why many people prefer the enzyme in supplement form.

The Research Behind Nattokinase

Nattokinase has been the subject of numerous research studies, particularly in Japan. Research has explored its enzymatic properties and various health applications. The 2000 FU dose in our formula reflects amounts used in clinical research.

Frequently Asked Questions

Why is there a warning about blood thinners? Nattokinase has fibrinolytic (clot-dissolving) activity, which means it should not be combined with medications that affect blood clotting. This could potentially increase bleeding risk.

Can I take this if I take aspirin daily? No. Aspirin is an antiplatelet medication, and combining it with nattokinase is not recommended. Consult your doctor.

What if I'm on blood pressure medication? You should not take this supplement without medical supervision if you're on blood pressure medication, as interactions may occur.

How long before surgery should I stop taking this? Stop at least 2 weeks before any scheduled surgery to allow the enzyme to clear your system.

Is this the same as eating natto? The enzyme is extracted from natto, but taking the supplement is not identical to eating the fermented food. However, it provides the nattokinase enzyme without the strong taste and texture of natto.

Can I take this with other Vitadefence products? Check that you're not duplicating vitamin D3 or selenium if taking multiple supplements. The Marine Collagen Multi and Liposomal D3 + K2 both contain vitamin D3.

Why vegan D3? Our D3 is sourced from algae rather than lanolin (sheep's wool), making it suitable for vegans while providing the same cholecalciferol form your body produces naturally.

Does this contain vitamin K2? No, this formula does not contain vitamin K2. However, natto (the food) is one of nature's richest sources of vitamin K2. If you want K2, consider our Liposomal D3 + K2 formula.

Can I take this if I have a thyroid condition? Consult your doctor first. The formula contains selenium, which contributes to normal thyroid function, but those with thyroid conditions should check with their healthcare provider.

Why only 1 capsule per day? The 2000 FU dose is substantial and represents a clinically relevant amount. More is not necessarily better with enzymes.

Combining with Other Supplements

Our Nattokinase Multi can potentially be combined with other Vitadefence products, but considerations include:

• Check vitamin D3 totals - This provides 110% NRV, so account for this if taking other D3 supplements
• Check selenium totals - This provides 100% NRV
• Avoid with other circulation-affecting supplements - Such as high-dose ginkgo, garlic supplements, or fish oil, without medical supervision
• Always consult your doctor when combining supplements, especially if on any medications

The Japanese Longevity Connection

Japan has one of the highest life expectancies in the world, and researchers have studied various aspects of the Japanese diet for insights into longevity. Natto is one of several traditional foods that has garnered scientific interest.

While we cannot attribute health outcomes to single foods or supplements, the traditional consumption of natto in regions of Japan known for longevity has made nattokinase a popular supplement worldwide.

Building a Heart-Healthy Lifestyle

Supplements work best as part of a comprehensive approach:

1. Balanced diet - Rich in vegetables, fruits, whole grains, and healthy fats
2. Regular physical activity - At least 150 minutes of moderate exercise weekly
3. Stress management - Meditation, yoga, or other relaxation techniques
4. Quality sleep - 7-9 hours nightly for most adults
5. Avoid smoking - One of the most important factors for cardiovascular health
6. Limit alcohol - Moderation is key
7. Regular health screenings - Monitor blood pressure, cholesterol, etc.
8. Stay hydrated - Adequate water intake supports circulation

Remember: no supplement can replace a healthy lifestyle or medical treatment when needed.

The Vitadefence Approach

We believe effective supplementation requires:

• Research-informed formulation - Ingredients and doses based on traditional use and studies
• Quality sourcing - Premium ingredients from trusted suppliers
• Comprehensive support - Multiple complementary ingredients, not just isolated compounds
• Safety first - Clear warnings and contraindications
• Transparency - Complete ingredient disclosure and honest information
• Realistic expectations - Supplements support wellness; they don't replace medical care

What Makes This Formula Unique

Several factors distinguish our Nattokinase Multi:

1. Meaningful nattokinase dose - 2000 FU per capsule, not a token amount
2. Comprehensive botanical blend - Eight different botanicals working synergistically
3. Immune support addition - Selenium and D3 for year-round immune health
4. Vegan-friendly - Including vegan D3 source (though contains soy)
5. One capsule daily - Simple, convenient dosing
6. GMP quality - Manufactured to high standards in the UK

Your Cardiovascular Wellness Journey

Whether you're proactively supporting your cardiovascular system, following a doctor's recommendation to support your wellness routine, or exploring traditional Japanese health wisdom, our Nattokinase Multi offers a comprehensive, carefully formulated approach.

The combination of nattokinase with complementary botanicals and essential nutrients creates a formula that addresses cardiovascular wellness from multiple angles—enzymatic support, antioxidant properties, and immune function.

Remember: This supplement is not suitable for everyone. The contraindications regarding blood pressure and blood thinning medications are serious. Always consult your healthcare provider before starting any new supplement, especially one affecting cardiovascular function.

If this formula is appropriate for you, consistent daily use combined with a healthy lifestyle offers the best approach to supporting your long-term wellness.