Amino Acid Multi: How to Use It in a Daily Performance Stack

Whether you're pushing through the final reps of a heavy session or looking to support recovery after a long run, your muscles rely on a steady supply of amino acids. Vitadefence Amino Acid Multi combines the three branched-chain amino acids (BCAAs) — leucine, isoleucine and valine — with citrulline malate, vitamin C and vitamin B6 in a refreshing lemon & lime formula. Designed to be taken during or after exercise, this 300 g powder provides 5.6 g of BCAAs per serving alongside evidence-backed nutrients that support normal energy metabolism and the reduction of tiredness and fatigue.

What are BCAAs and citrulline malate?

Branched-chain amino acids (BCAAs) are a group of three essential amino acids — leucine, isoleucine and valine — that the body cannot produce on its own. Unlike other amino acids, BCAAs are metabolised primarily in skeletal muscle rather than the liver, making them particularly relevant for exercise recovery and muscle protein synthesis. Leucine, in particular, is well-recognised in the scientific literature as a key trigger for muscle protein synthesis, with clinical studies often using doses around 2–3 g per serving to stimulate a measurable response (PubMed ID: 28515025).

Citrulline malate is a combination of the amino acid L-citrulline and malic acid. It has been studied for its potential to reduce perceived exertion during exercise and support ammonia clearance, with typical effective doses ranging from 6–8 g taken 60 minutes before activity (PubMed ID: 25601344). In Amino Acid Multi, citrulline malate is included at a level of approximately 1 g per serving, which is a moderate dose intended to complement the BCAA profile rather than serve as a standalone ergogenic aid.

Amino Acid Multi ingredients

Each 8 g serving (one flat scoop) provides:

• L-Leucine – 2.8 g
• L-Isoleucine – 1.4 g
• L-Valine – 1.4 g
• L-Citrulline Malate – 0.94 g
• Vitamin C – 37.6 mg (47% NRV)
• Vitamin B6 – 0.96 mg (69% NRV)
• Dextrose, natural flavouring, natural colour (turmeric extract), sweetener (sucralose), acidity regulator (citric acid)

Total BCAAs per serving: 5.6 g. The ratio of leucine to isoleucine and valine is approximately 2:1:1, which aligns with the ratio most commonly used in clinical research on muscle protein synthesis and exercise recovery.

How the formula was designed

Amino Acid Multi was formulated with a focus on practical, evidence-informed dosing. The 2:1:1 BCAA ratio is one of the most studied in sports nutrition, with leucine taking the lead as the primary anabolic signal. The inclusion of vitamin B6 and vitamin C is not incidental — both nutrients have authorised health claims under EU Regulation 1924/2006. Vitamin B6 contributes to normal energy-yielding metabolism and the reduction of tiredness and fatigue, while vitamin C contributes to the normal function of the immune system and the protection of cells from oxidative stress.

Citrulline malate was added at a dose that complements the BCAA profile without overwhelming the formula. The lemon & lime flavour, achieved with natural flavouring and a small amount of turmeric extract for colour, makes the powder easy to mix and pleasant to drink during or after exercise. Dextrose provides a small amount of carbohydrate to aid palatability and may help with the absorption of amino acids, though the total carbohydrate per serving is low.

The science — what's well-supported

Under EU Regulation 1924/2006, the following authorised health claims apply to the vitamins in Amino Acid Multi:

• Vitamin B6 contributes to normal energy-yielding metabolism, normal homocysteine metabolism, normal protein and glycogen metabolism, normal psychological function, the reduction of tiredness and fatigue, and the normal function of the immune system.
• Vitamin C contributes to normal collagen formation for the normal function of blood vessels, bones, cartilage, gums, skin and teeth; normal energy-yielding metabolism; normal function of the immune system; the protection of cells from oxidative stress; and the reduction of tiredness and fatigue.

Regarding BCAAs, a 2017 systematic review and meta-analysis published in the journal Nutrients (PubMed ID: 28515025) concluded that BCAA supplementation can reduce muscle soreness and markers of muscle damage after exercise, particularly when taken before or during exercise. The review noted that leucine content appears to be a key factor, with doses of 2 g or more per serving showing the most consistent benefits.

Citrulline malate has been studied primarily for its effects on exercise performance and perceived exertion. A 2015 study in the Journal of Strength and Conditioning Research (PubMed ID: 25601344) found that 8 g of citrulline malate taken one hour before upper-body resistance exercise reduced muscle soreness and improved performance. The dose in Amino Acid Multi is lower than this, so its effects should be viewed as supportive rather than primary.

How to take it

Mix one flat scoop (8 g) of powder with 250 ml of water or juice. Consume during or after exercise. Do not exceed one serving per day. Because the powder may settle during transit and storage, weighing the serving with a food scale is recommended for the most accurate measure. If you do not have a scale, use the scoop provided and level it off with a knife or spatula.

Amino Acid Multi is not a meal replacement. It is designed to be used alongside a balanced diet that meets your overall protein and energy needs.

Storage

Store in a cool, dry place, out of direct sunlight and out of reach of children. Keep the lid tightly closed after each use. Do not use if the inner seal is damaged or missing. The best before date is printed on the base of the pot.

Allergen and dietary information

Amino Acid Multi is suitable for vegetarians and vegans. It is Halal approved. The product is manufactured in a GMP-certified facility that handles a wide range of ingredients, but the formula itself does not contain gluten, wheat, dairy, soy, egg, fish, shellfish, tree nuts or peanuts. Always check the label for the most current allergen information.

Who should be cautious

Amino Acid Multi is intended for healthy adults who engage in regular physical activity. If you are pregnant, breastfeeding, have a medical condition (particularly kidney or liver disease), or are taking medication, consult a healthcare professional before use. Individuals with maple syrup urine disease (MSUD) should avoid BCAA supplements entirely. As with any supplement, discontinue use if you experience any adverse effects.

What pairs well with Amino Acid Multi

For those looking to build a more comprehensive supplement routine, Amino Acid Multi can be combined with other products from the Vitadefence range:

• Creatine Multi — Creatine monohydrate is one of the most researched supplements for strength and power output. Taking it alongside BCAAs can support both immediate performance and recovery. Read more in the Creatine Multi guide.
• Hemp Protein Multi — A complete plant protein source that provides additional amino acids to support muscle repair. Ideal for post-exercise meals or snacks. See the Hemp Protein Multi guide for details.
• L-Glutamine — Glutamine is the most abundant amino acid in the body and may support gut health and immune function during periods of heavy training. Learn more in the L-Glutamine guide.

You can also explore our bundle options to save on combined purchases.

Frequently asked questions

Can I take Amino Acid Multi on rest days?

Yes. While it is designed primarily for use during or after exercise, taking it on rest days may still support general recovery and provide the vitamins B6 and C, which contribute to normal energy metabolism and immune function. One serving per day is the maximum recommended dose.

Is this a complete protein source?

No. Amino Acid Multi contains only three essential amino acids (leucine, isoleucine and valine) plus citrulline malate. It does not provide all nine essential amino acids required for complete protein synthesis. It is best used as a targeted supplement alongside whole food protein sources or a complete protein powder like Hemp Protein Multi.

Can I take it with other supplements?

Yes. Amino Acid Multi can be taken alongside other Vitadefence products such as Creatine Multi and L-Glutamine. However, we recommend checking total vitamin intakes if you are taking other vitamin-containing supplements. The amounts of vitamin C (37.6 mg) and vitamin B6 (0.96 mg) per serving are modest and well within safe upper limits.

Does it need to be taken with food?

Not necessarily. Amino Acid Multi can be taken on its own mixed with water. However, consuming it alongside a meal that contains carbohydrates may enhance amino acid uptake and muscle protein synthesis. The small amount of dextrose in the formula provides a minimal carbohydrate source.

How long does one pot last?

Each 300 g pot contains 42 servings. If taken once daily, one pot lasts approximately six weeks. For best value, consider our bundle deals.

Is the lemon & lime flavour natural?

The flavouring is natural, and the yellow colour comes from turmeric extract. The sweetness is provided by sucralose, a non-nutritive sweetener that does not affect blood sugar levels.

Why Vitadefence

Vitadefence is a UK-based brand committed to transparency, quality and evidence-led formulation. Every product is manufactured in a GMP-certified facility and, where applicable, made by an Informed Manufacturer — meaning our production sites are regularly tested to the highest standards for banned substances. We use third-party testing to verify the identity and potency of our ingredients, and we never include proprietary blends that hide individual doses.

Our formulas are designed around the authorised health claims of the EU Register, ensuring that every nutrient listed on the label has a legitimate, science-backed role. We do not make exaggerated claims about "boosting immunity" or "detoxifying" the body. Instead, we provide clear, honest information so you can make informed decisions about your supplement routine.

We also offer free shipping on orders over £30 and a 30-day satisfaction guarantee. If you are not completely satisfied, we will refund your purchase — no questions asked. Read verified customer reviews on our reviews page and check our shipping policy for details.

Bottom line

Amino Acid Multi is a straightforward, no-nonsense BCAA supplement with added vitamin C and vitamin B6, designed to support recovery and energy metabolism during and after exercise. The 2:1:1 leucine-to-isoleucine/valine ratio is well-supported by research, and the inclusion of citrulline malate adds a complementary layer of support for exercise tolerance. While it is not a complete protein source, it serves a specific role in a targeted supplement routine — particularly when paired with a balanced diet and other evidence-based products like Creatine Multi or Hemp Protein Multi.

Buy Amino Acid Multi now and experience the difference that honest, evidence-led formulation makes.

This article is for educational purposes only and does not constitute medical advice. The authorised health claims cited are from the EU Register of Nutrition and Health Claims (EU Regulation 1924/2006). Individual results may vary. Always consult a healthcare professional before starting any new supplement, particularly if you have a medical condition or are taking medication. Vitadefence supplements are not intended to diagnose, treat, cure or prevent any disease.